Scientific achievements:
Activation of Si — H and S — C связей in silaparaffines under the action of transition metal complexes and ionic fluorides. Elaboration of effective catalysts for hydrocracking of alkanes and cycloalkanes based on Ziegler — Natta complexes and ligand deficient osmium clusters. Development of superelectrophilic systems of new types for activation and low-temperature transformations of alkanes and cycloalkanes. Hydrocarbon transformations of alkanes and cycloalkanes. Elaboration of selective syntheses of organic compounds from alkanes and cycloalkanes. The nature of new active superelectrophilic systems and mechanistic studies on superelectrophilic alkane activation. “Alkane-like” functionalizations of monofunctional organic compounds.
Some important publications:
1. I. S. Akhrem, A. V. Orlinkov. Polyhalomethanes Combined with Lewis Acids in Alkane Chemistry, Chem. Revs., 2007, 107, 2037-2079. (and references therein).
2. I. S. Akhrem, D. V. Avetisyan, S. V. Vitt, Р. V. Petrovskii. One-step tetrahydrofuran ring opening by saturated hydrocarbons and CO, Mendeleev Commun., 2005, 5, 185-187.
3. I. S. Akhrem, A. V. Orlinkov, S. V. Vitt, A. L Chistyakov. First examples of superelectrophile initiated iodination of alkanes and cycloalkanes, Tetrahedron Lett., 2002, 43, 1333-1335.
4. A. V. Orlinkov, I. S. Akhrem, S. V. Vitt. The First Efficient Carbonylation of Ethane with CO, Mendeleev Commun., 1999, 5, 198-199.
5. I. S. Akhrem, A. L. Chistyakov, N. P. Gambaryan, I. V. Stankevich, M. E. Vol’pin. Polyhalomethanes Combined with Aluminium Halides as Generators of Superelectrophiles of a Novel Type, J. Organomet. Chem., 1997, 536, 489-495.
6. I. S. Akhrem, A. V. Orlinkov. Low temperature alkane functionalization by classical and non classical (superelectrophilic) Friedel-Craft complexes, Uspekhi Khim., 1996, 65, 920-935.
7 I. Akhrem, I. Churilova, S. Bernadyuk, M. Vol’pin. An effective formylation of adamantane by the aprotic organic superacid CBr4·2AlBr3 under mild conditions, Tetrahedron Lett., 1996, 37, 5775-5778.
8. A. V. Chistyakov, I. V. Stankevich, I. S. Akhrem, N. P. Gambaryan, M. E. Vol’pin. Superelectrophiles generated in m Br2 nAlBr3 systems, Mendeleev Commun., 1996, 175-178.
9. I. Akhrem, S. Gudima, M. Vol’pin. Novel sulfur-containing inorganic syperelectrophiles - effective initiators of low-temperature cracking and isomerization of alkanes, Chem.- Eur. J. 1996, 2, 812-814.
10. I. S. Akhrem, A. V. Orlinkov, M. E. Vol’pin. A novel family of aprotic organic superacids for low temperature alkane and cycloalkane transformations, J. Chem. Soc., Chem. Commun, 1993, 671-673.
11. I. S. Akhrem, S. V. Reznichenko, N. M. Chistovalova, V. V. Grushin, M. E. Vol’pin. Osmium ligand deficient clusters as catalysts for liquid phase hydrocarbon transformations, Catal. Letters, 1993, 20, 275-286.
12. I. S. Akhrem, N. M. Chistovalova, M. F. Polubentseva, I. E. Pikersky, Yu. G. Dubinsky, M. E. Voi’pin. Carbonaceous fragments of osmium ligand deficient clusters that take part in alkane C-H and C-C bonds cleavage in the presence of molecular hydrogen, Catal. Letters. 1993, 19, 361-367.
13. I. S. Akhrem, M. E Vol’pin. Activation of С-С bonds in saturated hydrocarbons by metal complexes, Uspekhi Khim., 1990, 59, 1906-1930.
14. M. E. Vol’pin, I. S. Akhrem, A. V. Orlinkov. Aprotic organic superacids — effective reagents for transformations of alkanes and cycloalkanes under mild conditions, Nouveau Journal de Chimie, 1989, № 10/11, 13, 771–790.
15. M. E. Vol’pin, I. S. Akhrem, S. B. Reznichenko, V. V. Grushin. Activation of C-C bonds in alkanes and cycloalkanes by Ziegler–type system, J. Organomet. Chem., 1987, 334, № 1/2, с. 109–116.
16. J.-P Battioni, I. Artaud, D. Dupre, P. Leduc, I. Akhrem, D. Mansyu, J Fisher, R. Weiss, I. Morgenstern — Badarau. Reaction of a carbon equivalent of iodosylbezene with iron-porphirins: a ready access to N- alkylporphyrin complexes involving five-membered Fe-O-C=C-N metallocycles, J. Amer. Chem. Soc. 1986, 108, 5598–5607.
17. D. Mansyu, J.- P, Battioni, I. S. Akhrem, D. Dupre, J. Fisher, R. Weiss, I. Morgenstern–Badarau. Reaction of a carbon analogue of iodosylbenzene with iron- porphyrins: isolation and X-ray structure of iron (II) complex with O-C-O moieties inserted between two trans iron- nitrogen bonds, J. Amer. Chem. Soc., 1984, 106, 6112–6114.
18. I. S. Akhrem, N. M Chistivalova, H. M Safoyan, M. E. Vol’pin, I. I. Moiseev. Mechanistic aspects of Pd (II) chloride catalyzed cleavage of the Si — Ar bonds. An unusual character of substituents effects, J. Organometal. Chem., 1979, 178, 22–26.
19. I. S. Akhrem, N. M Chistivalova, E. I. Mysov, M. E. Vol’pin. The cleavage of Si-C bonds by transition metal compounds. Methylation and phenylation of olefins by organosilicon compounds in the presence of palladium salts, J. Organometal. Chem. 1974, 72, 163–170.
